Genetic determinants of human hypertension.

@article{Lifton1995GeneticDO,
  title={Genetic determinants of human hypertension.},
  author={Richard P. Lifton},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 19},
  pages={
          8545-51
        }
}
Hypertension is a common trait of multifactorial determination imparting an increased risk of myocardial infarction, stroke, and end-stage renal disease. The primary determinants of hypertension, as well as the factors which determine specific morbid sequelae, remain unknown in the vast majority of subjects. Knowledge that a large fraction of the interindividual variation in this trait is genetically determined motivates the application of genetic approaches to the identification of these… CONTINUE READING

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