Genetic determinants of common obesity and their value in prediction.

  title={Genetic determinants of common obesity and their value in prediction.},
  author={Ruth J. F. Loos},
  journal={Best practice & research. Clinical endocrinology & metabolism},
  volume={26 2},
Genome-wide association studies (GWAS) have revolutionised the discovery of genes for common traits and diseases, including obesity-related traits. In less then four years time, 52 genetic loci were identified to be unequivocally associated with obesity-related traits. This vast success raised hope and expectations that genetic information would become soon an integral part of personalised medicine. However, these loci have only small effects on obesity-susceptibility and explain just a… CONTINUE READING


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