Genetic determinants of Rous sarcoma virus particle size.

  title={Genetic determinants of Rous sarcoma virus particle size.},
  author={Neel K Krishna and Stephen J Campbell and Volker M. Vogt and John W Wills},
  journal={Journal of virology},
  volume={72 1},
The Gag proteins of retroviruses are the only viral products required for the release of membrane-enclosed particles by budding from the host cell. Particles released when these proteins are expressed alone are identical to authentic virions in their rates of budding, proteolytic processing, and core morphology, as well as density and size. We have previously mapped three very small, modular regions of the Rous sarcoma virus (RSV) Gag protein that are necessary for budding. These assembly… CONTINUE READING

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