Genetic determinants for n-butanol tolerance in evolved Escherichia coli mutants: cross adaptation and antagonistic pleiotropy between n-butanol and other stressors.

Abstract

Cross-tolerance and antagonistic pleiotropy have been observed between different complex phenotypes in microbial systems. These relationships between adaptive landscapes are important for the design of industrially relevant strains, which are generally subjected to multiple stressors. In our previous work, we evolved Escherichia coli for enhanced tolerance… (More)
DOI: 10.1128/AEM.01703-13

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@article{Reyes2013GeneticDF, title={Genetic determinants for n-butanol tolerance in evolved Escherichia coli mutants: cross adaptation and antagonistic pleiotropy between n-butanol and other stressors.}, author={Luis H Reyes and Ali S. Abdelaal and Katy C Kao}, journal={Applied and environmental microbiology}, year={2013}, volume={79 17}, pages={5313-20} }