Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity.

Abstract

Neuropsychiatric disorders characterized by behavioral disinhibition, including disorders of compulsivity (e.g. obsessive-compulsive disorder; OCD) and impulse-control (e.g. impulsive aggression), are severe, highly prevalent and chronically disabling. Treatment options for these diseases are extremely limited. The pathophysiological bases of disorders of… (More)
DOI: 10.1111/j.1471-4159.2012.07739.x

Topics

  • Presentations referencing similar topics