Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide.

  title={Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide.},
  author={Ant{\'o}nio Coutinho and Luciana Forni and Fritz Georg Melchers and Takehiko Watanabe},
  journal={European journal of immunology},
  volume={7 5},
Splenic B cells C57BL/10ScCr mice fail to respond to the mitogenic principle of lipopolysaccharide (LPS), and do not express a serologically defined "LPS receptor". In contrast, polyclonal B cell responses to both purified protein derivative of tuberculin and lipoprotein are conserved. 
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