Genetic control of susceptibility to experimental allergic encephalomyelitis and the Ag-B locus of rats.

Abstract

Injection of guinea pig spinal cord with complete Freund's adjuvant induces EAE in Lewis (Ag-B1) and DA (Ag-B4) rats, but not in rats of the BN (Ag-B3) strain. When BN is crossed with Lewis, susceptibility is determined by a gene linked to the Ag-B histocompatibility locus, but a much more complex mode of inheritance is involved when BN and DA rats are… (More)

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Cite this paper

@article{Gasser1975GeneticCO, title={Genetic control of susceptibility to experimental allergic encephalomyelitis and the Ag-B locus of rats.}, author={David Gasser and Joy Palm and N. K. Gonatas}, journal={Journal of immunology}, year={1975}, volume={115 2}, pages={431-3} }