Genetic control of parasite clearance leads to resistance to Plasmodium berghei ANKA infection and confers immunity

Abstract

Unprecedented cure after infection with the lethal Plasmodium berghei ANKA was observed in an F2 progeny generated by intercrossing the wild-derived WLA and the laboratory C57BL/6 mouse strains. Resistant mice were able to clear parasitaemia and establish immunity. The observed resistance was disclosed as a combinatorial effect of genetic factors derived… (More)
DOI: 10.1038/sj.gene.6364219

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@article{Campino2005GeneticCO, title={Genetic control of parasite clearance leads to resistance to Plasmodium berghei ANKA infection and confers immunity}, author={Susana G. Campino and S{\'e}bastien Bagot and M L Bergman and P. Almeida and N{\'e}stor Sep{\'u}lveda and Sylviane Pied and Carlos Penha-Gonçalves and Dan Holmberg and P. -A. Cazenave}, journal={Genes and Immunity}, year={2005}, volume={6}, pages={416-421} }