Genetic control of immune responsiveness to poly (LPro)--poly (LLys)-derived polypeptides by histocompatibility-linked immune response genes in the rat.

@article{Gnther1976GeneticCO,
  title={Genetic control of immune responsiveness to poly (LPro)--poly (LLys)-derived polypeptides by histocompatibility-linked immune response genes in the rat.},
  author={Eberhard G{\"u}nther and Edna Mozes and Erwin R{\"u}de and Michael Sela},
  journal={Journal of immunology},
  year={1976},
  volume={117 6},
  pages={2047-52}
}
In rats responsiveness to branched synthetic polypeptides carrying a Pro--L backbone, such as (T,G)-Pro--L or (Phe,G)-Pro-L and to Pro--L itself is controlled by Ir genes which are linked to the major histocompatibility genes. The level of antibody production to these polypeptides does not fall into strict high or low responder categories but covers the… CONTINUE READING