Genetic control of enzyme expression in Drosophila: a locus influencing tissue specificity of aldehyde oxidase.

@article{Dickinson1978GeneticCO,
  title={Genetic control of enzyme expression in Drosophila: a locus influencing tissue specificity of aldehyde oxidase.},
  author={W. Joseph Dickinson},
  journal={The Journal of experimental zoology},
  year={1978},
  volume={206 3},
  pages={333-41}
}
A natural genetic variant in Drosophila melanogaster with a highly tissue specific effect on the level of an enzyme (aldehyde oxidase) is described. This variant causes overproduction of the enzyme by a factor of 2- to 3-fold in paragonia (male accessory sex glands) while having no significant effect on the enzyme level in other tissues. This difference is controlled by a single genetic element in the vicinity of the aldehyde oxidase structural gene that operates in a strictly cis-active mode… CONTINUE READING

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