Genetic control of apomorphine-induced climbing behavior in two inbred mouse strains.

@article{Kendler1984GeneticCO,
  title={Genetic control of apomorphine-induced climbing behavior in two inbred mouse strains.},
  author={Kenneth S. Kendler and Kenneth L. Davis},
  journal={Brain research},
  year={1984},
  volume={293 2},
  pages={343-51}
}
Over a wide dose range (1-32 mg/kg), apomorphine-induced climbing behavior was significantly greater in the AKR/J than in the DBA/2J inbred mouse strain. A similar difference was found when apomorphine-induced stereotypy was examined. A cross-fostering study demonstrated that the strain difference in apomorphine-induced climbing behavior did not result from differences in post-natal rearing environment. After apomorphine administration, brain levels of the drug were similar in the two strains… CONTINUE READING