Genetic conjugation of components in two pneumococcal fusion protein vaccines enhances paediatric mucosal immune responses.

Abstract

Streptococcus pneumoniae colonises the upper respiratory tract and can cause pneumonia, meningitis and otitis media. Existing pneumococcal conjugate vaccines are expensive to produce and only protect against 13 of the 90+ pneumococcal serotypes; hence there is an urgent need for the development of new vaccines. We have shown previously in mice that… (More)
DOI: 10.1016/j.vaccine.2015.02.012

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Cite this paper

@article{Pope2015GeneticCO, title={Genetic conjugation of components in two pneumococcal fusion protein vaccines enhances paediatric mucosal immune responses.}, author={Caroline Pope and Elizabeth H Oliver and Jiangtao Ma and Claire D Langton Hewer and Tim J. Mitchell and Adam Finn}, journal={Vaccine}, year={2015}, volume={33 14}, pages={1711-8} }