Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome.

@article{Arai2008GeneticCO,
  title={Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome.},
  author={Eri Arai and Saori Ushijima and Hitoshi Tsuda and Hiroyuki Fujimoto and F. Hosoda and Tatsuhiro Shibata and Tadashi Kondo and Issei Imoto and Johji Inazawa and Setsuo Hirohashi and Yae Kanai},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2008},
  volume={14 17},
  pages={5531-9}
}
PURPOSE The aim of this study was to clarify genetic and epigenetic alterations occurring during renal carcinogenesis. EXPERIMENTAL DESIGN Copy number alterations were examined by array-based comparative genomic hybridization analysis using an array harboring 4,361 bacterial artificial chromosome clones, and DNA methylation alterations on CpG islands of the p16, human MutL homologue 1, von Hippel-Lindau, and thrombospondin 1 genes and the methylated in tumor (MINT-1, MINT-2, MINT-12, MINT-25… CONTINUE READING
22 Citations
29 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Lossofchromo - some 9 p is an independent prognostic factor in patientswithclear cell renalcellcarcinoma

  • EccherA BrunelliM, GobboS
  • ModPathol
  • 2008

Similar Papers

Loading similar papers…