Genetic characterization of type 2a canine parvoviruses from Taiwan reveals the emergence of an Ile324 mutation in VP2

@inproceedings{Lin2013GeneticCO,
  title={Genetic characterization of type 2a canine parvoviruses from Taiwan reveals the emergence of an Ile324 mutation in VP2},
  author={Chao-Nan Lin and Chi-Hsien Chien and M. C. Chiou and L. -L. Chueh and Meng-Yu Hung and Han-Siang Hsu},
  booktitle={Virology Journal},
  year={2013}
}
Canine parvovirus 2 (CPV 2) is a major infectious cause of mortality in puppies. The characteristic symptom of CPV 2 disease is intestinal hemorrhage with severe bloody diarrhea. Soon after CPV was first recognized in the late 1970s, the original virus, CPV 2, was replaced in the canine population by strains carrying minor antigenic variants (termed 2a, 2b, and 2c) of the VP2 gene that could be distinguished using monoclonal antibodies and molecular analyses. Here, we provide an updated… CONTINUE READING
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