Genetic cause of autosomal recessive hereditary nephropathy in the English Cocker Spaniel.

@article{Davidson2007GeneticCO,
  title={Genetic cause of autosomal recessive hereditary nephropathy in the English Cocker Spaniel.},
  author={Ashley Greene Davidson and Rebecca Jane Hesley Bell and George E. Lees and Clifford Elliot Kashtan and George S. Davidson and Keith Eugene Murphy},
  journal={Journal of veterinary internal medicine},
  year={2007},
  volume={21 3},
  pages={
          394-401
        }
}
BACKGROUND Autosomal recessive hereditary nephropathy (ARHN) in the English Cocker Spaniel is caused by a type IV collagen defect, but the underlying mutation is unknown. ANIMALS One hundred thirty-four English Cocker Spaniels (12 with ARHN, 8 obligate carriers, and 114 others), 3 mixed breed dogs with X-linked hereditary nephropathy (XLHN), and 7 other dogs without hereditary nephropathy were included. METHODS Diagnosis of ARHN was based on transmission electron microscopy and… CONTINUE READING
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