Genetic basis of transcriptome diversity in Drosophila melanogaster.

  title={Genetic basis of transcriptome diversity in Drosophila melanogaster.},
  author={Wen Huang and Mary Anna Carbone and Michael M. Magwire and Jason Peiffer and Richard F. Lyman and Eric A. Stone and Robert R H Anholt and Trudy F C Mackay},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={112 44},
Understanding how DNA sequence variation is translated into variation for complex phenotypes has remained elusive but is essential for predicting adaptive evolution, for selecting agriculturally important animals and crops, and for personalized medicine. Gene expression may provide a link between variation in DNA sequence and organismal phenotypes, and its abundance can be measured efficiently and accurately. Here we quantified genome-wide variation in gene expression in the sequenced inbred… CONTINUE READING
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