Genetic basis of neurological tumours.

  title={Genetic basis of neurological tumours.},
  author={David N Louis and Bernd R. Seizinger},
  journal={Bailliere's clinical neurology},
  volume={3 2},
Neurological tumours are common neoplasms of both adults and children. Recent studies have begun to delineate the genetic abnormalities that underlie such tumours, and have implicated two classes of genes, oncogenes and tumour suppressor genes. Most investigations have focused on those astrocytomas that affect the cerebral hemispheres of adults, since these are the most common and malignant brain tumours. The high-grade astrocytomas that affect adults, such as glioblastoma multiforme, often… CONTINUE READING
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