Genetic bases and phenotypic consequences of high-temperature adaptation in Escherichia coli

@inproceedings{Verdugo2014GeneticBA,
  title={Genetic bases and phenotypic consequences of high-temperature adaptation in Escherichia coli},
  author={Alejandra Rodriguez Verdugo},
  year={2014}
}
Beneficial mutations play an essential role in bacterial adaptation, yet little is known about their fitness effects across genetic backgrounds and environments. One prominent example of bacterial adaptation is antibiotic resistance. Until recently, the paradigm has been that antibiotic resistance is selected by the presence of antibiotics because resistant mutations are associated with fitness costs in antibiotic free environments. In this study we show that it is not always the case… CONTINUE READING

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