Genetic associations of the response to inhaled corticosteroids in children during an asthma exacerbation.

@article{Keskin2016GeneticAO,
  title={Genetic associations of the response to inhaled corticosteroids in children during an asthma exacerbation.},
  author={Ozlem Keskin and {\"U}nal Uluca and Esra Birben and Yavuz Coşkun and Mehmet Yasar Ozkars and Mehmet K{\"u}rşad Keskin and Ercan Kuçukosmanoglu and Omer Kalayci},
  journal={Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology},
  year={2016},
  volume={27 5},
  pages={507-13}
}
BACKGROUND Genetic associations of the response to inhaled corticosteroids (ICSs) during an asthma exacerbation are unknown. OBJECTIVE To evaluate the role of genetic variants in the therapeutic response to high-dose ICS in children with moderate-to-severe asthma exacerbations. METHODS Eighty-two children (56 boys/26 girls, mean age 9.6 ± 3.2 years) with moderate-severe asthma exacerbation were genotyped for eight single-nucleotide polymorphisms that were a priori associated with ICS… CONTINUE READING
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