Genetic association studies in female reproduction: from candidate-gene approaches to genome-wide mapping.

@article{Zhao2013GeneticAS,
  title={Genetic association studies in female reproduction: from candidate-gene approaches to genome-wide mapping.},
  author={Han Xiao Zhao and Zi-Jiang Chen},
  journal={Molecular human reproduction},
  year={2013},
  volume={19 10},
  pages={644-54}
}
Many genetic association studies have been performed to investigate disorders of female reproduction, such as polycystic ovary syndrome, premature ovarian failure and endometriosis. These disorders typically manifest heterogeneously, and their pathogeneses are influenced by polygenic and environmental factors. Researchers evaluating these genetic associations have chosen candidate genes related to hormone action, steroid biosynthesis, inflammatory cytokines and autoimmune factors. Several of… CONTINUE READING

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Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene

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