Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene

Abstract

A recent genome-wide association study revealed a variant (rs2431697) in an intergenic region, between the pituitary tumor-transforming 1 (PTTG1) and microRNA (miR-146a) genes, associated with systemic lupus erythematosus (SLE) susceptibility. Here, we analyzed with a case–control design this variant and other candidate polymorphisms in this region together… (More)
DOI: 10.1038/gene.2011.84

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