Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population.

@article{Zhou2011GeneticAO,
  title={Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population.},
  author={Xujie Zhou and Xiao-lan Lu and Ji-cheng Lv and Hai-zhen Yang and Lian-xiang Qin and Ming-Hui Zhao and Yin Su and Zhan-guo Li and Hong Zhang},
  journal={Annals of the rheumatic diseases},
  year={2011},
  volume={70 7},
  pages={1330-7}
}
OBJECTIVE Recent genome-wide association studies suggested the PRDM1-ATG5 gene region as a systemic lupus erythematosus (SLE)-associated locus both in Caucasian and Chinese populations; however, the candidate gene was still obscure and the possible functional significance needed to be determined. METHODS In this study, by a multistage integrative strategy, the authors first performed a case-control association study involving 1745 individuals in the Chinese population by genotyping nine… CONTINUE READING

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