Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome.

@article{Hulkkonen2001GeneticAB,
  title={Genetic association between interleukin-10 promoter region polymorphisms and primary Sj{\"o}gren's syndrome.},
  author={Janne Hulkkonen and Marja I Pertovaara and Jaakko A Antonen and Nina Lahdenpohja and Amos I Pasternack and Mikko A. Hurme},
  journal={Arthritis and rheumatism},
  year={2001},
  volume={44 1},
  pages={176-9}
}
OBJECTIVE To determine whether the haplotypes formed on the basis of single-base-exchange polymorphisms at positions -1082, -819, or -592 of the interleukin-10 (IL-10) gene predispose subjects to primary Sjögren's syndrome (SS). METHODS The frequency of IL-10 polymorphisms was analyzed in 62 patients with primary SS and in 400 healthy subjects. These data were assessed for correlations with the concentration of IL-10 in the plasma. RESULTS The frequency of the IL-10 GCC haplotype (G at… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
36 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 36 extracted citations

Similar Papers

Loading similar papers…