Genetic aspects of the etiology and treatment of asthma.

@article{Meurer2006GeneticAO,
  title={Genetic aspects of the etiology and treatment of asthma.},
  author={John R. Meurer and James V. Lustig and Howard J. Jacob},
  journal={Pediatric clinics of North America},
  year={2006},
  volume={53 4},
  pages={715-25}
}
This article provides a clinical review of the genetic aspects of the etiology and treatment of asthma for pediatric practitioners who are experienced in asthma diagnosis and management but lack expertise in genetics and immunology. Asthma is caused by the interaction of genetic susceptibility with environmental factors. The asthmatic response is characterized by elevated production of IgE, cytokines, and chemokines; mucus hypersecretion; airway obstruction; eosinophilia; and enhanced airway… CONTINUE READING