Genetic architecture for susceptibility to gout in the KARE cohort study

  title={Genetic architecture for susceptibility to gout in the KARE cohort study},
  author={Jimin Shin and Younyoung Kim and Minyoung Kong and Chaeyoung Lee},
  journal={Journal of Human Genetics},
This study aimed to identify functional associations of cis-regulatory regions with gout susceptibility using data resulted from a genome-wide association study (GWAS), and to show a genetic architecture for gout with interaction effects among genes within each of the identified functions. The GWAS was conducted with 8314 control subjects and 520 patients with gout in the Korea Association REsource cohort. However, genetic associations with any individual nucleotide variants were not discovered… CONTINUE READING
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Survey of current trends for diagnosis and treatment in Korean gout patients

M. C. Hochberg, A. J. Silman, +8 authors Y. D. Bae
J . Rheum . Dis . • 2011

Uric acid transport and disease.

The Journal of clinical investigation • 2010

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.

Proceedings of the National Academy of Sciences of the United States of America • 2009

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