Genetic approaches to modeling anxiety in animals.

  title={Genetic approaches to modeling anxiety in animals.},
  author={Laura Helen Jacobson and John F Cryan},
  journal={Current topics in behavioral neurosciences},
Anxiety disorders are a growing health problem world-wide. However, the causative factors, etiology, and underlying mechanisms of anxiety disorders, as for most psychiatric disorders, remain relatively poorly understood. The current status of clinical research indicates that anxiety traits and anxiety disorder in man have a genetic component, and therefore genetic modeling in animals is a logical approach to gain a greater insight into their neurobiology. However, it is also clear that the… CONTINUE READING