Genetic and physical interactions involving the yeast nuclear cap-binding complex.

@article{Fortes1999GeneticAP,
  title={Genetic and physical interactions involving the yeast nuclear cap-binding complex.},
  author={Puri Fortes and Joanna Kufel and Maarten Fornerod and Maria Polycarpou-Schwarz and Don Lafontaine and David Tollervey and Iain W Mattaj},
  journal={Molecular and cellular biology},
  year={1999},
  volume={19 10},
  pages={6543-53}
}
Yeast strains lacking the yeast nuclear cap-binding complex (yCBC) are viable, although impaired in growth. We have taken advantage of this observation to carry out a genetic screen for components that show synthetic lethality (SL) with a cbp20-Delta cbp80-Delta double mutation. One set of SL interactions was due to mutations that were complemented by components of U1 small nuclear RNP (snRNP) and the yeast splicing commitment complex. These interactions confirm the role of yCBC in commitment… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 85 references

Similar Papers

Loading similar papers…