Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome

@article{Hirschtritt2017GeneticAP,
  title={Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome},
  author={M. Hirschtritt and S. Darrow and C. Illmann and L. Osiecki and M. Grados and P. Sandor and Y. Dion and R. King and D. Pauls and C. Budman and D. Cath and E. Greenberg and G. Lyon and D. Yu and L. McGrath and W. McMahon and P. C. Lee and K. Delucchi and J. Scharf and C. Mathews},
  journal={Psychological Medicine},
  year={2017},
  volume={48},
  pages={279 - 293}
}
Background The unique phenotypic and genetic aspects of obsessive-compulsive (OCD) and attention-deficit/hyperactivity disorder (ADHD) among individuals with Tourette syndrome (TS) are not well characterized. Here, we examine symptom patterns and heritability of OCD and ADHD in TS families. Method OCD and ADHD symptom patterns were examined in TS patients and their family members (N = 3494) using exploratory factor analyses (EFA) for OCD and ADHD symptoms separately, followed by latent class… Expand
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