Genetic and pharmacological manipulations that alter metabolism suppress seizure-like activity in Drosophila.


There is increasing evidence that alterations in metabolism can affect seizure susceptibility in a wide range of organisms. In order to investigate the link between metabolism and seizures, we took advantage of a group of Drosophila mutants, the Bang-sensitive (BS) paralytics, which are 3-10 times more susceptible to seizure-like activity (SLA) than wild… (More)
DOI: 10.1016/j.brainres.2012.12.007


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