Genetic and other diseases in the pottery of Tumaco‐La Tolita culture in Colombia–Ecuador

@article{Bernal2006GeneticAO,
  title={Genetic and other diseases in the pottery of Tumaco‐La Tolita culture in Colombia–Ecuador},
  author={Jesus Poveda Bernal and Ignacio Brice{\~n}o},
  journal={Clinical Genetics},
  year={2006},
  volume={70}
}
The people of Tumaco‐La Tolita culture inhabited the borders of present‐day Colombia and Ecuador. Already extinct by the time of the Spaniards arrival, they left a huge collection of pottery artifacts depicting everyday life; among these, disease representations were frequently crafted. In this article, we present the results of the personal examination of the largest collections of Tumaco‐La Tolita pottery in Colombia and Ecuador; cases of Down syndrome, achondroplasia, mucopolysaccharidosis I… 
Possible case of sirenomelia in the Tumaco‐Tolita pottery pre‐Columbian culture, 2000 years before the epidemic focus of sirenomelia in Cali‐Colombia
TLDR
A pottery sample from the Tumaco-Tolita culture close to 2,000 years old is presented with a possible sirenomelia that presents phenotypical features like fused lower limbs, probably constituting the oldest evidence of this disease in the pre-Hispanic LatinAmerican and past world.
Achondroplasia among ancient populations of mesoamerica and South America: Iconographic and Archaeological Evidence.
TLDR
The hypothesis that the individuals with short stature were somehow associated with the political and religious power elite in the Mayan state society of Mexico and Guatemala is presented.
Achondroplasia among ancient populations of mesoamerica and South America: Iconographic and Archaeological Evidence.
TLDR
The hypothesis that the individuals with short stature were somehow associated with the political and religious power elite in Mayan state society of Mexico and Guatemala is presented.
Ethical and economic considerations of rare diseases in ethnic minorities: the case of mucopolysaccharidosis VI in Colombia
TLDR
The ethical and economic considerations, regarding both direct and indirect costs, of a high-cost orphan disease in a marginalised minority population in a developing country are discussed.
Determination of genotypic and clinical characteristics of Colombian patients with mucopolysaccharidosis IVA
TLDR
Clinical variables and genotypic analysis were similar to those reported for other world populations, and Bioinformatics tools showed differences in the binding interactions of mutant proteins with the G6S ligand, in regard the wild-type GALNS.
Design and applications of gene therapy vectors for mucopolysaccharidosis in Colombia
TLDR
The authors argue in favor of doing research in gene therapy, because it is proving to be the solution for many monogenic diseases, and therefore there is a need of people with good command of GT all over the world to make good use of that therapy especially for ex-vivo treatments.
Study of Glutathione-S-transferase (gstm1 and gstt1) Gene Polymorphisms in Down Syndrome Patients
TLDR
Examination of artifacts from the Tumaco-La Tolita culture suspected that certain figurines depicted individuals with Trisomy 21, making these potteries the earliest evidence for the syndrome, characterized by dysmorphic facies.
...
1
2
3
4
5
...

References

SHOWING 1-9 OF 9 REFERENCES
Genetic defects as recorded in the pottery of the Moche culture of Peru
TLDR
The part of Peru known as the Moche area is formed by a strip of desert along the coast in the northern part of the country, and among these ceramics are also a wide variety depicting disfigured individuals and individuals with genetic defects.
The real earliest historical evidence of Down syndrome
TLDR
It is thought that the first ‘‘artist’’ to depict this syndrome in human history that has reached to us, was the anonymous person whomade this small sculpture of an infant with Down syndrome, in the very beginnings of the authors' Era.
Memorias de la misio´n Arqueoló gica Espan˜ola en el Ecuador. Tomo I. Madrid: Ministerio Asuntos Exteriores
  • 1979
Ancient peoples and places. Colombia
  • Thames and Hudson, Londres,
  • 1965
Ancient peoples and places. Colombia: Thames and Hudson
  • 1965
Anales de la Universidad Central
  • 1927
Estudio Esmeraldeños
  • Anales de la Universidad Central. Quito 1927:
  • 1927
Estudio Esmeraldeños . Anales de la Universidad Central
  • Quito
  • 1927