Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.

@article{Li2006GeneticAN,
  title={Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.},
  author={Ming Li and Jesus F Salazar-Gonzalez and Cynthia A. Derdeyn and Lynn Morris and Carolyn Williamson and James E Robinson and Julie M. Decker and Yingying Li and Maria G Salazar and Victoria Polonis and Koleka Mlisana and Salim S. Abdool Karim and Kunxue Hong and Kelli Greene and Miroslawa Bilska and Jintao Zhou and Susan K Allen and Elwyn Nachanya Chomba and Joseph Mulenga and Cheswa M. Vwalika and Feng Gao and Ming Juan Zhang and Bette T Korber and Eric Hunter and Beatrice H. Hahn and David C. Montefiori},
  journal={Journal of virology},
  year={2006},
  volume={80 23},
  pages={11776-90}
}
A standard panel of subtype C human immunodeficiency virus type 1 (HIV-1) Env-pseudotyped viruses was created by cloning, sequencing, and characterizing functional gp160 genes from 18 acute and early heterosexually acquired infections in South Africa and Zambia. In general, the gp120 region of these clones was shorter (most evident in V1 and V4) and less glycosylated compared to newly transmitted subtype B viruses, and it was underglycosylated but no different in length compared to chronic… CONTINUE READING
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