Genetic and neurobiological basis of alcohol-seeking behavior.

@article{Li1994GeneticAN,
  title={Genetic and neurobiological basis of alcohol-seeking behavior.},
  author={T. K. Li and Lawrence Lumeng and William J H Mcbride and James M Murphy},
  journal={Alcohol and alcoholism},
  year={1994},
  volume={29 6},
  pages={697-700}
}
Through selective breeding, rat lines exhibiting high and low alcohol drinking preference have been developed as useful animal models for studying the neurobiological basis of alcohol-seeking behavior. The identified differences between lines in neurotransmitter functioning allows the evaluation of receptor agonist/antagonist compounds that might be efficacious in the treatment of alcohol craving and dependence.