Genetic and hormonal regulation of the death of peptidergic neurons in the Drosophila central nervous system.


To understand the role apoptosis plays in nervous system development and to gain insight into the mechanisms by which steroid hormones regulate neuronal apoptosis, we investigated the death of a set of peptidergic neurons in the CNS of the fruitfly Drosophila melanogaster. Typically, apoptosis in Drosophila is induced by the expression of the genes reaper… (More)