Genetic and functional evaluation of the level of inbreeding of the Westran pig: a herd with potential for use in xenotransplantation.

Abstract

BACKGROUND The Westran pig has been purposely inbred for use in xenotransplantation. The herd originated in the wild from a limited gene pool and has been inbred by repeated full-sib matings for nine generations. METHODS The aim of this study was to evaluate the level of inbreeding by functional assays, such as bi-directional MLR and reciprocal skin… (More)

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