Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence.

@article{Opriessnig2006GeneticAE,
  title={Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence.},
  author={Tanja Opriessnig and Nicola McKeown and E M Zhou and X. J. Meng and Patrick G. Halbur},
  journal={The Journal of general virology},
  year={2006},
  volume={87 Pt 10},
  pages={2923-32}
}
There are marked differences in the clinical expression of diseases associated with porcine circovirus type 2 (PCV2) in the field. The objective of this study was to compare the sequences and pathogenicity of PCV2 isolates from field cases with and without PCV2-associated lesions. Forty-two specific-pathogen-free (SPF) pigs were assigned randomly to three groups of 14 pigs each. At 7 weeks of age, group 1 pigs were mock-inoculated with saline, group 2 pigs were inoculated with PCV2-4838… CONTINUE READING

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