Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology.

@article{Booij2015GeneticAE,
  title={Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology.},
  author={Linda Booij and Richard E. Tremblay and Moshe Szyf and C. Benkelfat},
  journal={Journal of psychiatry & neuroscience : JPN},
  year={2015},
  volume={40 1},
  pages={5-18}
}
BACKGROUND Despite more than 60 years of research in the role of serotonin (5-HT) in psychopathology, many questions still remain. From a developmental perspective, studies have provided more insight into how 5-HT dysfunctions acquired in utero or early in life may modulate brain development. This paper discusses the relevance of the developmental role of 5-HT for the understanding of psychopathology. We review developmental milestones of the 5-HT system, how genetic and environmental 5-HT… CONTINUE READING

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