Genetic and dietary salt contributors to insulin resistance in Dahl salt-sensitive (S) rats

Abstract

Insulin resistance has been extensively investigated during the past decade because of its proposed role in initiating a cluster of cardiovascular risk factors including hypertension. Insulin resistance is an inherited genetic trait that precedes hypertension in Dahl salt-sensitive (S) rats, and is not present in Dahl salt-resistant (R) rats. Owing to the… (More)
DOI: 10.1186/1475-2840-7-7

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