Genetic and antigenic requirements for induction of T helper cells for anti-Sendai virus-specific antibody production.

Abstract

T helper cells for the promotion of Sendai virus-specific antibody production were generated in vitro. They could be stimulated by infectious, UV light-inactivated or fusion-negative Sendai virus, which had to be presented by adherent cells. Induction of T helper cells was virus-specific and required H-2 IA region compatibility between T cells and antigen… (More)

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