Genetic and antigenic diversity of human caliciviruses (HuCVs) using RT-PCR and new EIAs.

@article{Jiang1996GeneticAA,
  title={Genetic and antigenic diversity of human caliciviruses (HuCVs) using RT-PCR and new EIAs.},
  author={Xi Jiang and David O. Matson and W David Cubitt and Mary K. Estes},
  journal={Archives of virology. Supplementum},
  year={1996},
  volume={12},
  pages={251-62}
}
RT-PCR using primers from conserved regions of calicivirus genomes, followed by sequencing, permits characterization of genetic variation within the family. EIAs based on baculovirus-expressed viral capsid proteins and hyperimmune antisera against the capsid proteins were developed to detect HuCV antigens and antibodies. Serologic surveys using recombinant… CONTINUE READING