Genetic and Hormonal Regulation of Tryptophan–Kynurenine Metabolism

  title={Genetic and Hormonal Regulation of Tryptophan–Kynurenine Metabolism},
  author={G. Oxenkrug},
  journal={Annals of the New York Academy of Sciences},
  • G. Oxenkrug
  • Published 2007
  • Psychology, Medicine
  • Annals of the New York Academy of Sciences
  • Impairment of cognition that is caused by (or associated with) vascular factors has been termed vascular cognitiveimpairment (VCI). The hallmark of VCI is an impairment of brain executive, or planning, functions caused by inflammatory changes of brain microvessels. VCI is characterized by impairment of the executive function and is distinct from Alzheimer's‐type and multi‐infarct dementias, although VCI might overlap with Alzheimer's disease. This review focuses on the possible contribution of… CONTINUE READING
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