Genetic and Functional Diversification of Small RNA Pathways in Plants

@article{Xie2004GeneticAF,
  title={Genetic and Functional Diversification of Small RNA Pathways in Plants},
  author={Zhixin Xie and Lisa K. Johansen and Adam M. Gustafson and Kristin D. Kasschau and Andrew D. Lellis and Daniel Zilberman and Steven E. Jacobsen and James C. Carrington},
  journal={PLoS Biology},
  year={2004},
  volume={2}
}
Multicellular eukaryotes produce small RNA molecules (approximately 21–24 nucleotides) of two general types, microRNA (miRNA) and short interfering RNA (siRNA). They collectively function as sequence-specific guides to silence or regulate genes, transposons, and viruses and to modify chromatin and genome structure. Formation or activity of small RNAs requires factors belonging to gene families that encode DICER (or DICER-LIKE [DCL]) and ARGONAUTE proteins and, in the case of some siRNAs, RNA… 

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