Genetic analysis of three patients with an 18p- syndrome and dystonia.

@article{Klein1999GeneticAO,
  title={Genetic analysis of three patients with an 18p- syndrome and dystonia.},
  author={Christoph Klein and Curtis E. Page and Peter A Lewitt and Mark Forrest Gordon and Deborah de Leon and Yasser Awaad and Xandra O Breakefield and Mitchell F. Brin and Laurie Ozelius},
  journal={Neurology},
  year={1999},
  volume={52 3},
  pages={649-51}
}
Some patients with an 18p- syndrome show dystonia, and a focal dystonia gene has been mapped to chromosome 18p. The authors evaluated the extent of the deletion in three patients with an 18p- syndrome and dystonia using 14 DNA markers on 18p. A common deleted area, covering the DYT7 locus, places the putative dystonia gene between the telomere of 18p and… CONTINUE READING