Genetic analysis of thirty-three platelet polypeptides detected in two-dimensional polyacrylamide gels.

@article{Hanash1986GeneticAO,
  title={Genetic analysis of thirty-three platelet polypeptides detected in two-dimensional polyacrylamide gels.},
  author={Samir M Hanash and James V. Neel and Leslie J. Baier and Barnett B. Rosenblum and W Niezgoda and David P. Markel},
  journal={American journal of human genetics},
  year={1986},
  volume={38 3},
  pages={352-60}
}
Two-dimensional gel electrophoresis followed by silver-staining was utilized to visualize platelet polypeptides for genetic analysis. A subset of 33 polypeptides that were most suited for scoring was selected. Families consisting of father-mother-child trios were studied. Thirty-six polypeptides of a total of 1,413 scored in children's gels exhibited the combination of a normal and a variant polypeptide. The observed index of heterozygosity of 2.55% is comparable to our previously reported… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…