Genetic analysis of the principal genes related to prostate cancer: a review.

@article{AlvarezCubero2013GeneticAO,
  title={Genetic analysis of the principal genes related to prostate cancer: a review.},
  author={Maria Jesus Alvarez-Cubero and Mar{\'i}a Soledad Ibarra Saiz and Luis Javier Martinez-Gonzalez and Juan Carlos Flores Alvarez and Jose Antonio Lorente and Jos{\'e} Manuel de C{\'o}zar},
  journal={Urologic oncology},
  year={2013},
  volume={31 8},
  pages={
          1419-29
        }
}
Prostate cancer is one of the most common leading causes of cancer death in men. Attributable to many genetic linkage and genome-wide association studies (GWAS) around the world, several high-penetrance genetic variants have been identified. Many polymorphisms in genes, such as ELAC2 (locus HPC2), RNase L (locus hereditary prostate cancer 1 gene [HPC1]), and MSR1 have been recognized as important genetic factors that confer an increased risk of developing prostate cancer in many populations. A… CONTINUE READING
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