Genetic analysis of the karyotype instability in natural wine yeast strains.

@article{Carro2001GeneticAO,
  title={Genetic analysis of the karyotype instability in natural wine yeast strains.},
  author={David Carro and Benjam{\'i}n Pi{\~n}a},
  journal={Yeast},
  year={2001},
  volume={18 16},
  pages={1457-70}
}
Yeast strains isolated from the wild may show high rates of changes in their karyotypes during vegetative growth. We analysed over 500 karyotypes from mitotic and meiotic derivatives of strain DC5, which has a chromosome rearrangement rate of 8.2 x 10(-3) changes/generation. About 70% of the meiotic derivatives of DC5 had low rearrangement rates, with an average of 5.8 x 10(-4) changes/generation, suggesting that karyotype instability behaved as a dominant phenotype. Diploid derivatives with… CONTINUE READING