Genetic analysis of the contribution of IL10 to systemic lupus erythematosus.

  title={Genetic analysis of the contribution of IL10 to systemic lupus erythematosus.},
  author={Marta E. Alarc{\'o}n-Riquelme and Aron Lindqvist and Inger Jonasson and Bo Johanneson and S Sandino and Jorge Alcocer-Varela and J. Javier Rainer Granados and Helga Kristj{\'a}nsd{\'o}ttir and Gerdur Gr{\"o}ndal and Elisabet Svenungsson and Ingrid Lundberg and Kristj{\'a}n Steinsson and Lars Klareskog and Gunnar K Sturfelt and Lennart Truedsson and Donato Alarc{\'o}n-Segovia and Ulf Gyllensten},
  journal={The Journal of rheumatology},
  volume={26 10},
OBJECTIVE To study the contribution of the IL10 gene to the susceptibility to systemic lupus erythematosus (SLE). METHODS Analysis by fluorescent-semiautomated genotyping of a dinucleotide repeat located in the promoter region of the IL10 locus (microsatellite G). RESULTS No significant difference was found in the frequencies of the microsatellite alleles of 330 Mexican patients with SLE compared to 368 controls from the same population. Two-point linkage analyses were carried out using 13… CONTINUE READING