Genetic analysis of neuronal ionotropic glutamate receptor subunits.

@article{Granger2011GeneticAO,
  title={Genetic analysis of neuronal ionotropic glutamate receptor subunits.},
  author={Adam J. Granger and John R. Gray and Wei Lu and Roger A Nicoll},
  journal={The Journal of physiology},
  year={2011},
  volume={589 17},
  pages={4095-101}
}
In the brain, fast, excitatory synaptic transmission occurs primarily through AMPA- and NMDA-type ionotropic glutamate receptors. These receptors are composed of subunit proteins that determine their biophysical properties and trafficking behaviour. Therefore, determining the function of these subunits and receptor subunit composition is essential for understanding the physiological properties of synaptic transmission. Here, we discuss and evaluate various genetic approaches that have been used… CONTINUE READING
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In contrast , the GluN2A and GluN2B NMDA receptor subunits regulate synaptic AMPA receptor content , both during synaptic development and plasticity .
In contrast , the GluN2A and GluN2B NMDA receptor subunits regulate synaptic AMPA receptor content , both during synaptic development and plasticity .
In contrast , the GluN2A and GluN2B NMDA receptor subunits regulate synaptic AMPA receptor content , both during synaptic development and plasticity .
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