Genetic analysis of intestinal cholesterol absorption in inbred mice.

  title={Genetic analysis of intestinal cholesterol absorption in inbred mice.},
  author={Margaret A Schwarz and Daphne L. Davis and Binje Vick and D. W. Russell},
  journal={Journal of lipid research},
  volume={42 11},
A genetic mapping strategy was employed to identify chromosomal regions harboring genes that influence the absorption of intestinal cholesterol in the mouse. Analysis of seven inbred strains of male mice (129P3, AKR, BALB/c, C3H/He, C57BL/6, DBA/2, and SJL, all from Jackson Laboratories) revealed substantial differences in their abilities to absorb a bolus of cholesterol delivered by gavage. Crosses between high (AKR, 129) and low (DBA/2, SJL) absorbing strains revealed evidence for the… CONTINUE READING
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Chromosomal or - ganziation of candidate genes involved in cholesterol gallstone formation : A murine gallstone map

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