Genetic analysis of childhood germ cell tumors with comparative genomic hybridization.

@article{Schneider2001GeneticAO,
  title={Genetic analysis of childhood germ cell tumors with comparative genomic hybridization.},
  author={Dominik T. Schneider and Amy E Schuster and Michael K. Fritsch and Gabriele Calaminus and Dieter Harms and Ulrich Goebel and Elizabeth J Perlman},
  journal={Klinische Padiatrie},
  year={2001},
  volume={213 4},
  pages={
          204-11
        }
}
BACKGROUND Germ Cell Tumors (GCTs) in children and adolescents constitute a clinically and histologically heterogeneous group of tumors. Compared to GCTs in adults, the numbers of GCTs in children analyzed with cytogenetic and molecular genetic techniques is limited. However, the data available to date reveal a pattern of cytogenetic aberrations different from that in adults. Comparative genomic hybridization (CGH) is a valuable technique for the genetic profiling of tumors that allows… CONTINUE READING

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