Genetic analysis of adrenal absence: agenesis and aplasia.

  title={Genetic analysis of adrenal absence: agenesis and aplasia.},
  author={Tobias Else and Gary D Hammer},
  journal={Trends in endocrinology and metabolism: TEM},
  volume={16 10},
The adrenal cortex shares a common embryological heritage with the gonad and kidney: all are derived from components of the urogenital ridge. Adrenocortical specification from this embryonic structure and the ultimate organogenesis of the adrenal gland are directed by the sequential expression of transcriptional regulators, with later development being additionally mediated by endocrine hormones that regulate organ maintenance and tissue differentiation. Recent advancements in the field of… CONTINUE READING

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